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KMID : 1134120210240040409
Journal of Breast Cancer
2021 Volume.24 No. 4 p.409 ~ p.416
Pyoderma Gangrenosum Mimicking Wound Infection after Breast Cancer Surgery
Kim Da-Bin

Hur Sung-Mo
Lee Jae-Seok
Chin Su-Sie
Lim Cheol-Wan
Kim Zi-Sun
Abstract
Postoperative pyoderma gangrenosum (PPG) is rare, and its diagnosis is often delayed because of its wound infection-mimicking course. A 53-year-old breast cancer patient who underwent breast-conserving surgery of the right breast presented with fever, leukocytosis, C-reactive protein elevation, and redness of the right breast on postoperative day (POD) 3. The breast wound showed desquamation with painful ulcerative changes from POD 6, and fever was sustained under antibiotic administration. Wound irrigation was attempted; however, inflammatory skin damage progressed to involvement of the entire skin overlying the breast. With clinical suspicion of PPG, skin biopsy and systemic corticosteroid initiation were performed on POD 12. Wound damage progression ceased, and the systemic inflammation subsided. The patient underwent split-thickness skin grafting under intravenous corticosteroid administration, and the wound healed after 30 days. PPG is a rare clinical scenario. Early diagnosis is critical to avoid unnecessary treatment and aggravation of the surgical wound.
KEYWORD
Breast, Breast neoplasms, Pyoderma gangrenosum
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